Following a remarkable and historic Champions league comeback, Juventus have suffered their first defeat in the 2017/2018 Serie A season.
The Old Ladies have remained unbeaten in as much as 27 games and they looked set to extend the winning streak only to have it halted by Genoa who defeated them 2-0 at the Stadio Luigi Ferraris.
Ronaldo was remarkably missing from the encounter as he was rested after a very demanding Champions League game against Atletico Madrid that saw him score a hat-trick to usher Juventus into the quarter finals.
Juventus looked to have taken the lead from a Dybala strike in the 55th minutes, but for the VAR technology that cancelled the goal, even as a free-kick was awarded against Juve for off-side play.
Genoa continued pressing for the winner and had a penalty appeal denied by VAR after threatening Juventus backline.
But after 72nd minute of action, Goran Pandev turned in an assist that ensured that Stefano Sturaro netted the opener to see Genoa lead Juventus by 1-0.
With 10 minutes left on the clock the home-side further compounded Juventus woes after Pandev scored from a Cristian Kouame pass.
Juventus will hope to bounce back from the defeat even as they get set to Face Ajax in the quarter finals of the Champions League.